Regulatory
GVAPO
Part:BBa_K2986003:Design
Designed by: SUSTech_Shenzhen Group: iGEM19_SUSTech_Shenzhen (2019-10-05)
light-switchable transactivator
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
How can we coupled this light-switch system with gene coded for the cytokines, which may stay in the cytosol or secrete to the outside of the cells. Whether changing another kind of cells can affect the effect of this system.
Source
This light-switch transgene system is form the lab of Xue Wang, Xianjun Chen & Yi Yang, they published Spatiotemporal control of gene expression by a light-switchable transgene system in Nature Methods 2012.